Question about printing problems--what to do?

With several recent printer problems (e-reserve or other articles) not printing correctly at the student printers,and also not printing sometimes at the reference desk, but then fine when printed from my office computer (third time being the charm) I was wondering is there something to be checked on the printer setup that we can do? If so, could some details be provided? If not, is it best to put in a help desk request or follow another procedure? Thanks.